Structure of PDB 4p7x Chain A Binding Site BS01

Receptor Information
>4p7x Chain A (length=286) Species: 266835 (Mesorhizobium japonicum MAFF 303099) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PQFEKGATTRILGVVQLDQRRLTDDLAVLAKSNFSSEYSDFACGRWEFCM
LRNQSGKQEEQRVVVHETPALATPLGQSLPYLNELLDNHFDRDSIRYARI
IRISENACIIPHRDYLELEGKFIRVHLVLDTNEKCSNTEENNIFHMGRGE
IWFLDASLPHSAGCFSPTPRLHLVVDIEGTRSLEEVAINVEQPSARNATV
DTRKEWTDETLESVLGFSEIISEANYREIVAILAKLHFFHKVHCVDMYGW
LKEICRRRGEPALIEKANSLERFYLIDRAAGEVMTY
Ligand information
Ligand IDCO
InChIInChI=1S/Co/q+2
InChIKeyXLJKHNWPARRRJB-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Co+2]
CACTVS 3.341[Co++]
FormulaCo
NameCOBALT (II) ION
ChEMBL
DrugBankDB14205
ZINC
PDB chain4p7x Chain A Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4p7x Refined Regio- and Stereoselective Hydroxylation of l-Pipecolic Acid by Protein Engineering of l-Proline cis-4-Hydroxylase Based on the X-ray Crystal Structure.
Resolution1.3 Å
Binding residue
(original residue number in PDB)		H106 D108 H154
Binding residue
(residue number reindexed from 1)		H112 D114 H160
Annotation score1
Enzymatic activity
Enzyme Commision number 1.14.11.56: L-proline cis-4-hydroxylase.
Gene Ontology
Molecular Function
GO:0016706 2-oxoglutarate-dependent dioxygenase activity
GO:0046872 metal ion binding
GO:0051213 dioxygenase activity
Biological Process
GO:0018193 peptidyl-amino acid modification

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Molecular Function
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Biological Process
External links
PDB RCSB:4p7x, PDBe:4p7x, PDBj:4p7x
PDBsum4p7x
PubMed25171735
UniProtQ989T9|P4H_RHILO L-proline cis-4-hydroxylase (Gene Name=mlr6283)

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