Structure of PDB 4p6w Chain A Binding Site BS01
Receptor Information
>4p6w Chain A (length=252) Species:
9606
(Homo sapiens) [
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PQLTPTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAAV
KWAKAIPGFRNLHLDDQMTLLQYSWMALMAFALGWRSYRQSSANLLYFAP
DLIINEQRMTLPCMYDQCKHMLYVSSELHRLQVSYEEYLCMKVLLLLSTI
PKDGLKSQELFDEIRMTYIKELGAAIVAREGNSSQNWQRFYQLTKLLDSM
HEVVENLLNYCFQTFLDKTMSIEFPEMLAEIITNQIPKYSNGNIKKLLFH
QK
Ligand information
>4p6w Chain B (length=12) Species:
9606
(Homo sapiens) [
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ANALLRYLLDKD
Receptor-Ligand Complex Structure
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PDB
4p6w
Structures and mechanism for the design of highly potent glucocorticoids.
Resolution
1.951 Å
Binding residue
(original residue number in PDB)
I572 V575 K579 L589 M593 Q597 M752 E755 I756 N759
Binding residue
(residue number reindexed from 1)
I47 V50 K54 L64 M68 Q72 M227 E230 I231 N234
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:4p6w
,
PDBe:4p6w
,
PDBj:4p6w
PDBsum
4p6w
PubMed
24763108
UniProt
P04150
|GCR_HUMAN Glucocorticoid receptor (Gene Name=NR3C1)
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