Structure of PDB 4p2r Chain A Binding Site BS01

Receptor Information

>4p2r Chain A (length=180) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

IKEEHTIIQAEFYLLPDKRGEFMFDFDGDEIFHVDIEKSETIWRLEEFAK
FASFEAQGALANIAVDKANLDVMKERSNNTPDANVAPEVTVLSRSPVNLG
EPNILICFIDKFSPPVVNVTWLRNGRPVTEGVSETVFLPRDDHLFRKFHY
LTFLPSTDDFYDCEVDHWGLEEPLRKHWEF

Ligand information

>4p2r Chain C (length=13) Species: 32630 (synthetic construct) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

ANGVAFFLTPFKA

Receptor-Ligand Complex Structure

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Structure summary

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PDB	4p2r Deconstructing the Peptide-MHC Specificity of T Cell Recognition.
Resolution	3.295 Å
Binding residue (original residue number in PDB)	Q9 E11 S53 N62 V65 N69
Binding residue (residue number reindexed from 1)	Q9 E11 S53 N62 V65 N69

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Biological Process
GO:0006955	immune response
GO:0019882	antigen processing and presentation

	Cellular Component
GO:0016020	membrane
GO:0042613	MHC class II protein complex

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Biological Process

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Cellular Component

External links

PDB	RCSB:4p2r, PDBe:4p2r, PDBj:4p2r
PDBsum	4p2r
PubMed	24855945
UniProt	P04224\|HA22_MOUSE H-2 class II histocompatibility antigen, E-K alpha chain

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