Structure of PDB 4p2q Chain A Binding Site BS01

Receptor Information
>4p2q Chain A (length=180) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IKEEHTIIQAEFYLLPDKRGEFMFDFDGDEIFHVDIEKSETIWRLEEFAK
FASFEAQGALANIAVDKANLDVMKERSNNTPDANVAPEVTVLSRSPVNLG
EPNILICFIDKFSPPVVNVTWLRNGRPVTEGVSETVFLPRDDHLFRKFHY
LTFLPSTDDFYDCEVDHWGLEEPLRKHWEF
Ligand information
>4p2q Chain C (length=14) Species: 32630 (synthetic construct) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ADGLAYFRSSFKGG
Receptor-Ligand Complex Structure
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PDB4p2q Deconstructing the Peptide-MHC Specificity of T Cell Recognition.
Resolution3.3 Å
Binding residue
(original residue number in PDB)		Q9 E11 A52 S53 N62 V65 N69
Binding residue
(residue number reindexed from 1)		Q9 E11 A52 S53 N62 V65 N69
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

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Biological Process
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Cellular Component
External links
PDB RCSB:4p2q, PDBe:4p2q, PDBj:4p2q
PDBsum4p2q
PubMed24855945
UniProtP04224|HA22_MOUSE H-2 class II histocompatibility antigen, E-K alpha chain

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