Structure of PDB 4ozf Chain A Binding Site BS01

Receptor Information

>4ozf Chain A (length=181) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

IVADHVASYGVNLYQSYGPSGQYTHEFDGDEQFYVDLGRKETVWCLPVLR
QFRFDPQFALTNIAVLKHNLNSLIKRSNSTAATNEVPEVTVFSKSPVTLG
QPNILICLVDNIFPPVVNITWLSNGHSVTEGVSETSFLSKSDHSFFKISY
LTLLPSAEESYDCKVEHWGLDKPLLKHWEPE

Ligand information

>4ozf Chain J (length=13) Species: 4565 (Triticum aestivum) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

APQPELPYPQPGS

Receptor-Ligand Complex Structure

Global view

Local view

Structure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

PDB	4ozf T-cell receptor recognition of HLA-DQ2-gliadin complexes associated with celiac disease.
Resolution	2.7 Å
Binding residue (original residue number in PDB)	Y9 R52 F54 F58 N62 L66 H68 N69 S72 L73 R76
Binding residue (residue number reindexed from 1)	Y9 R53 F54 F58 N62 L66 H68 N69 S72 L73 R76

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Biological Process
GO:0006955	immune response
GO:0019882	antigen processing and presentation

	Cellular Component
GO:0016020	membrane
GO:0042613	MHC class II protein complex

View graph for
Biological Process

View graph for
Cellular Component

External links

PDB	RCSB:4ozf, PDBe:4ozf, PDBj:4ozf
PDBsum	4ozf
PubMed	24777060
UniProt	P01909\|DQA1_HUMAN HLA class II histocompatibility antigen, DQ alpha 1 chain (Gene Name=HLA-DQA1)

[Back to BioLiP]