Structure of PDB 4oh6 Chain A Binding Site BS01
Receptor Information
>4oh6 Chain A (length=242) Species:
9606
(Homo sapiens) [
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PIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAK
ALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSAMLYFAPDLVF
NEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDG
LKNQKFFDELRMNYIKELDRIIASCSRRFYQLTKLLDSVQPIARELHQFA
FDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFHTQ
Ligand information
>4oh6 Chain B (length=9) Species:
9606
(Homo sapiens) [
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YIFDLFYKR
Receptor-Ligand Complex Structure
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PDB
4oh6
Identification of a new androgen receptor (AR) co-regulator BUD31 and related peptides to suppress wild-type and mutated AR-mediated prostate cancer growth via peptide screening and X-ray structure analysis.
Resolution
3.56 Å
Binding residue
(original residue number in PDB)
V713 V716 Q733 M734 I737 Q738 E893 E897
Binding residue
(residue number reindexed from 1)
V43 V46 Q63 M64 I67 Q68 E216 E220
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:4oh6
,
PDBe:4oh6
,
PDBj:4oh6
PDBsum
4oh6
PubMed
25091737
UniProt
P10275
|ANDR_HUMAN Androgen receptor (Gene Name=AR)
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