Structure of PDB 4oh5 Chain A Binding Site BS01
Receptor Information
>4oh5 Chain A (length=242) Species:
9606
(Homo sapiens) [
Search protein sequence
] [
Download receptor structure
] [
Download structure with residue number starting from 1
] [
View receptor structure
]
PIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAK
ALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSAMLYFAPDLVF
NEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDG
LKNQKFFDELRMNYIKELDRIIASCSRRFYQLTKLLDSVQPIARELHQFA
FDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFHTQ
Ligand information
>4oh5 Chain B (length=9) [
Search peptide sequence
] [
Download ligand structure
] [
Download structure with residue number starting from 1
] [
View ligand structure
]
GAFQNLFQS
Receptor-Ligand Complex Structure
Global view
Local view
Structure summary
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
PDB
4oh5
Identification of a new androgen receptor (AR) co-regulator BUD31 and related peptides to suppress wild-type and mutated AR-mediated prostate cancer growth via peptide screening and X-ray structure analysis.
Resolution
2.0 Å
Binding residue
(original residue number in PDB)
V716 K720 Q733 M734 Q738 M894 E897
Binding residue
(residue number reindexed from 1)
V46 K50 Q63 M64 Q68 M217 E220
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:4oh5
,
PDBe:4oh5
,
PDBj:4oh5
PDBsum
4oh5
PubMed
25091737
UniProt
P10275
|ANDR_HUMAN Androgen receptor (Gene Name=AR)
[
Back to BioLiP
]
