Structure of PDB 4ofu Chain A Binding Site BS01
Receptor Information
>4ofu Chain A (length=241) Species:
9606
(Homo sapiens) [
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PIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAK
ALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSAMLYFAPDLVF
NEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDG
LKNQKFFDELRMNYIKELDRIIASCSRRFYQLTKLLDSVQPIARELHQFT
FDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFHT
Ligand information
>4ofu Chain B (length=8) Species:
32630
(synthetic construct) [
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SAFSRYYT
Receptor-Ligand Complex Structure
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PDB
4ofu
Identification of a new androgen receptor (AR) co-regulator BUD31 and related peptides to suppress wild-type and mutated AR-mediated prostate cancer growth via peptide screening and X-ray structure analysis.
Resolution
2.12 Å
Binding residue
(original residue number in PDB)
V716 K720 Q733 M734 I737 Q738 E893 E897
Binding residue
(residue number reindexed from 1)
V46 K50 Q63 M64 I67 Q68 E216 E220
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:4ofu
,
PDBe:4ofu
,
PDBj:4ofu
PDBsum
4ofu
PubMed
25091737
UniProt
P10275
|ANDR_HUMAN Androgen receptor (Gene Name=AR)
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