Structure of PDB 4ofr Chain A Binding Site BS01
Receptor Information
>4ofr Chain A (length=243) Species:
9606
(Homo sapiens) [
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PIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAK
ALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSAMLYFAPDLVF
NEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDG
LKNQKFFDELRMNYIKELDRIIAPTSCSRRFYQLTKLLDSVQPIARELHQ
FTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFHT
Ligand information
>4ofr Chain B (length=8) Species:
32630
(synthetic construct) [
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SSFRDWYT
Receptor-Ligand Complex Structure
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PDB
4ofr
Identification of a new androgen receptor (AR) co-regulator BUD31 and related peptides to suppress wild-type and mutated AR-mediated prostate cancer growth via peptide screening and X-ray structure analysis.
Resolution
2.26 Å
Binding residue
(original residue number in PDB)
K720 D731 Q733 M734 I737 Q738 M894 E897
Binding residue
(residue number reindexed from 1)
K50 D61 Q63 M64 I67 Q68 M219 E222
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:4ofr
,
PDBe:4ofr
,
PDBj:4ofr
PDBsum
4ofr
PubMed
25091737
UniProt
P10275
|ANDR_HUMAN Androgen receptor (Gene Name=AR)
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