Structure of PDB 4oez Chain A Binding Site BS01
Receptor Information
>4oez Chain A (length=242) Species:
9606
(Homo sapiens) [
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QPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWA
KALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSAMLYFAPDLV
FNEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVD
GLKNQKFFDELRMNYIKELDRIIASCSRRFYQLTKLLDSVQPIARELHQF
TFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFHT
Ligand information
>4oez Chain B (length=8) Species:
32630
(synthetic construct) [
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SAFSRLYT
Receptor-Ligand Complex Structure
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PDB
4oez
Identification of a new androgen receptor (AR) co-regulator BUD31 and related peptides to suppress wild-type and mutated AR-mediated prostate cancer growth via peptide screening and X-ray structure analysis.
Resolution
1.8 Å
Binding residue
(original residue number in PDB)
V716 K720 Q733 M734 I737 Q738 E893 M894 E897
Binding residue
(residue number reindexed from 1)
V47 K51 Q64 M65 I68 Q69 E217 M218 E221
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:4oez
,
PDBe:4oez
,
PDBj:4oez
PDBsum
4oez
PubMed
25091737
UniProt
P10275
|ANDR_HUMAN Androgen receptor (Gene Name=AR)
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