Structure of PDB 4o8j Chain A Binding Site BS01

Receptor Information
>4o8j Chain A (length=341) Species: 70601 (Pyrococcus horikoshii OT3) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MITIDGSYGEGGGQILRTSVALSTITGEPVRIVNIRANRPNPGLRPQHLH
AILALKHLANAEVKGAHVGSRELVFIPKKLEAKEISIDIGTAGSITLVLQ
ALLPAMVFAREKVKFRITGGTDVSWSPPVDYLSNVTLFALEKIGIHGEIR
VIRRGHYPKGGGIVEGYVEPWNEKRELVAKEYSRIIKIEGISHATNLPSH
VAERQARAAKDELLQLKVPIEIRTEISRSIGPGSGIVVWAETDCLRLGGD
ALGKKGKPAEIVGKEAAQELLDQLKPGHCVDKFLGDQLIPFLAFSGGVIW
VSEITNHLKTNIWVVESFLGRIFDVDGNVGEPGKIRVIRRV
Ligand information
Receptor-Ligand Complex Structure
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PDB4o8j Structure of RNA 3'-phosphate cyclase bound to substrate RNA.
Resolution2.04 Å
Binding residue
(original residue number in PDB)		G13 R17 R36 R39 P40 Q47 H48 T91 A92 G93 S94 V123 S124 W125 Y157 P158
Binding residue
(residue number reindexed from 1)		G13 R17 R36 R39 P40 Q47 H48 T91 A92 G93 S94 V123 S124 W125 Y157 P158
Enzymatic activity
Catalytic site (original residue number in PDB) E10 H307
Catalytic site (residue number reindexed from 1) E10 H307
Enzyme Commision number 6.5.1.4: RNA 3'-terminal-phosphate cyclase (ATP).
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0003963 RNA-3'-phosphate cyclase activity
GO:0005524 ATP binding
GO:0016874 ligase activity
Biological Process
GO:0006396 RNA processing
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4o8j, PDBe:4o8j, PDBj:4o8j
PDBsum4o8j
PubMed25161314
UniProtO59198|RTCA_PYRHO RNA 3'-terminal phosphate cyclase (Gene Name=rtcA)

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