Structure of PDB 4o1v Chain A Binding Site BS01

Receptor Information
>4o1v Chain A (length=141) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SGKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSGANDKLKWCLRVNPKG
LDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQRAYRF
VQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQD
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4o1v SPOP Promotes Tumorigenesis by Acting as a Key Regulatory Hub in Kidney Cancer.
Resolution2.0 Å
Binding residue
(original residue number in PDB)
Y87 E118 Y123 K129 D130 W131 G132
Binding residue
(residue number reindexed from 1)
Y62 E93 Y98 K104 D105 W106 G107
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:4o1v, PDBe:4o1v, PDBj:4o1v
PDBsum4o1v
PubMed24656772
UniProtO43791|SPOP_HUMAN Speckle-type POZ protein (Gene Name=SPOP)

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