Structure of PDB 4nw2 Chain A Binding Site BS01

Receptor Information
>4nw2 Chain A (length=173) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EFETIERFMDCRIGRKGATGATTTIYAVEADGDPNAGFEKNKEPGEIQYL
IKWKGWSHIHNTWETEETLKQQNVRGMKKLDNYKKKDQETKRWLKNASPE
DVEYYNCQQELTDDLHKQYQIVERIIAHSNQKSAAGYPDYYCKWQGLPYS
ECSWEDGALISKKFQACIDEYFS
Ligand information
>4nw2 Chain B (length=12) Species: 1348507 (Influenza A virus (A/swine/Henan/1/2010(H3N2))) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
PKQKRRTARSKV
Receptor-Ligand Complex Structure
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PDB4nw2 Structural basis for histone mimicry and hijacking of host proteins by influenza virus protein NS1.
Resolution1.9 Å
Binding residue
(original residue number in PDB)		A290 T293 Y295 W322 W325 D408 D425
Binding residue
(residue number reindexed from 1)		A21 T24 Y26 W53 W56 D139 D156
Enzymatic activity
Enzyme Commision number 3.6.4.12: DNA helicase.
External links
PDB RCSB:4nw2, PDBe:4nw2, PDBj:4nw2
PDBsum4nw2
PubMed24853335
UniProtO14646|CHD1_HUMAN Chromodomain-helicase-DNA-binding protein 1 (Gene Name=CHD1)

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