Structure of PDB 4nub Chain A Binding Site BS01

Receptor Information
>4nub Chain A (length=361) Species: 83333 (Escherichia coli K-12) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MEYQLTLNWPDFLERHWQKRPVVLKRGFNNFIDPISPDELAGLAMESEVD
SRLVSHQDGKWQVSHGPFESYDHLGETNWSLLVQAVNHWHEPTAALMRPF
RELPDWRIDDLMISFSVPGGGVGPHLDQYDVFIIQGTGRRRWRVGAALLQ
VDPFEAIIDEELEPGDILYIPPGFPHEGYALENAMNYSVGFRAPNTRELI
SGFADYVLQRELGGNYYSDPDVPPRAHPADVLPQEMDKLREMMLELINQP
EHFKQWFGEFISQSRHELDIAPPEPPYQPDEIYDALKQGEVLVRLGGLRV
LRIGDDVYANGEKIDSPHRPALDALASNIALTAENFGDALEDPSFLAMLA
ALVNSGYWFFE
Ligand information
Ligand IDFE
InChIInChI=1S/Fe/q+3
InChIKeyVTLYFUHAOXGGBS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[Fe+3]
FormulaFe
NameFE (III) ION
ChEMBL
DrugBankDB13949
ZINC
PDB chain4nub Chain A Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4nub Structure and Functional Analysis of YcfD, a Novel 2-Oxoglutarate/Fe(2+)-Dependent Oxygenase Involved in Translational Regulation in Escherichia coli.
Resolution2.7 Å
Binding residue
(original residue number in PDB)		H125 D127 H187
Binding residue
(residue number reindexed from 1)		H125 D127 H176
Annotation score1
Enzymatic activity
Enzyme Commision number 1.14.11.47: [50S ribosomal protein L16]-arginine 3-hydroxylase.
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0008198 ferrous iron binding
GO:0016706 2-oxoglutarate-dependent dioxygenase activity
GO:0042803 protein homodimerization activity
GO:0046872 metal ion binding
GO:0051213 dioxygenase activity
Biological Process
GO:0043687 post-translational protein modification

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Molecular Function
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Biological Process
External links
PDB RCSB:4nub, PDBe:4nub, PDBj:4nub
PDBsum4nub
PubMed24530688
UniProtP27431|ROXA_ECOLI Ribosomal protein uL16 3-hydroxylase (Gene Name=roxA)

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