Structure of PDB 4nod Chain A Binding Site BS01
Receptor Information
>4nod Chain A (length=190) Species:
9606
(Homo sapiens) [
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SVLASCPKKPVSSYLRFSKEQLPIFKAQNPDAKTTELIRRIAQRWRELPD
SKKKIYQDAYRAEWQVYKEEISRFKEQLTPSQIMSLEKEIMDKHLKRKAM
TKKKELTLLGKPKRPRSAYNVYVAERFQEAKGDSPQEKLKTVKENWKNLS
DSEKELYIQHAKEDETRYHNEMKSWEEQMIEVGRKDLLRR
Ligand information
>4nod Chain C (length=22) [
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ttggggtatggggcttggutgg
Receptor-Ligand Complex Structure
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PDB
4nod
Distinct structural features of TFAM drive mitochondrial DNA packaging versus transcriptional activation.
Resolution
2.897 Å
Binding residue
(original residue number in PDB)
L58 L65 T77 R140 M143 K146 Y162 Q179 K186 W189
Binding residue
(residue number reindexed from 1)
L15 L22 T34 R97 M100 K103 Y119 Q136 K143 W146
Binding affinity
PDBbind-CN
: Kd=7.1nM
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:4nod
,
PDBe:4nod
,
PDBj:4nod
PDBsum
4nod
PubMed
24435062
UniProt
Q00059
|TFAM_HUMAN Transcription factor A, mitochondrial (Gene Name=TFAM)
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