Structure of PDB 4nha Chain A Binding Site BS01

Receptor Information
>4nha Chain A (length=234) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LYVIGMVLTTPLPDELRKLYPPEDTTRCFGILTAKPIPQIPVYTRSGEVT
ISIELKKSGFMLSLQMLELITRLHQYIFSHILRLSAYCVLPLNVTLDIDF
KFMEDIEKSTKYTKETPFVFKLEDYQDAVIIPRYRNFDQPHRFYVADVYT
DLTPLSKFPSPEYETFAEYYKTKYNLDLTNLNQPLLDVDHTSSRLNLLTP
KQILVPELCAIHPIPASLWRKAVCLPSILYRLHC
Ligand information
Receptor-Ligand Complex Structure
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PDB4nha A Phosphate-Binding Pocket within the Platform-PAZ-Connector Helix Cassette of Human Dicer.
Resolution3.401 Å
Binding residue
(original residue number in PDB)		Y926 R927 F950 F958 Y961 Y962 Y966 I1022
Binding residue
(residue number reindexed from 1)		Y134 R135 F158 F166 Y169 Y170 Y174 I203
Enzymatic activity
Enzyme Commision number 3.1.26.3: ribonuclease III.
Gene Ontology

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Molecular Function
External links
PDB RCSB:4nha, PDBe:4nha, PDBj:4nha
PDBsum4nha
PubMed24486018
UniProtQ9UPY3|DICER_HUMAN Endoribonuclease Dicer (Gene Name=DICER1)

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