Structure of PDB 4nh0 Chain A Binding Site BS01

Receptor Information
>4nh0 Chain A (length=861) Species: 471852 (Thermomonospora curvata DSM 43183) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SANMTLTSLLHIDNPYNLDPAVLWRPRPQRNRLRVPIGLDADGRPLELDI
KESAQGGMGPHGLCIGATGSGKSELLRTLVLALAMTHSPEVLNFVLVDFK
GGATFLGMEGLRHVSAIITNLEEELPLVDRMYDALHGEMVRRQEHLRHSG
NYASLRDYEKARMEGAPLPPMPTLFIVLDEFSELLSAKPDFAELFVMIGR
LGRSLGVHLLLASQRLEEGKLRGLDTHLSYRIGLRTFSAMESRVVLGVPD
AYELPPSPGNGYLKFATEPLVRFKAAYVSGPVDEESESLFDVVVRQLAGH
GPEPHQIWLPPLDVPPTLDELLPPLSPSAAHGYTADGWEWRGRLHAVVGL
VDRPFDQRRDPYWLDLSGGAGHVGVAGGPQTGKSTMLRTLITSLALLHTP
QEVQFYCLDFGGGTLAGLAELPHVGSVATRLDADRIRRTVAEVSALLEQR
EQEFTERGIDSMATYRRLRATGEYAGDGFGDVFLVVDNWLTLRQDYEALE
DSITQLAARGLGYGIHVVLSSNKWSEFRTSIRDLLGTKLELRLGDPYESE
VDRKKAANVPENRPGRGLTRDGYHFLTALPRIDGDTSAETLTEGIATTVK
TIREAWHGPTAPPVRMLPNVLPAAQLPSAAESGTRIPIGIDEDSLSPVYL
DFNTDPHFLVFGDTECGKSNLLRLITAGIIERYTPQQARLIFIDYSRSLL
DVATTEHQIGYAASSTAASSLVRDIKGAMEARLPPPDLTPEQLRSRSWWT
GAELFLVVDDYEMVATSDNPLRPLAELLPQARDIGLHLIIARSMGGAGRA
LYEPIIQRIKEMASPGLVMSGNKDEGILLGNVKPHKLPQGRGYFVERRSG
TRLIQTAYRES
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain4nh0 Chain A Residue 1402 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4nh0 Substrates Control Multimerization and Activation of the Multi-Domain ATPase Motor of Type VII Secretion.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		S838 G865
Binding residue
(residue number reindexed from 1)		S384 G411
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003677 DNA binding
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity

View graph for
Molecular Function
External links
PDB RCSB:4nh0, PDBe:4nh0, PDBj:4nh0
PDBsum4nh0
PubMed25865481
UniProtD1A4G7|ECCC_THECD ESX secretion system protein EccC (Gene Name=eccC)

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