Structure of PDB 4ngg Chain A Binding Site BS01
Receptor Information
>4ngg Chain A (length=267) Species:
9606
(Homo sapiens) [
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QPCYLYVIGMVLTTPLPDELNFRRRKLYPPEDTTRCFGILTAKPIPQIPH
FPVYTRSGEVTISIELAASGFMLSLQMLELITRLHQYIFSHILRLEYCVL
PLNVVNDSTLDIDFKFMEDIEKSEARIGIPSTKYTKETPFVFKLEDYQDA
VIIPRYRNFDQPHRFYVADVYTDLTPLSKFPSPEYETFAEYYKTKYNLDL
TNLNQPLLDVDHTSSRLNLLTPRRKAKWESLQNKQILVPELCAIHPIPAS
LWRKAVCLPSILYRLHC
Ligand information
>4ngg Chain B (length=13) [
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agcgaauucgcuu
.............
Receptor-Ligand Complex Structure
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PDB
4ngg
A Phosphate-Binding Pocket within the Platform-PAZ-Connector Helix Cassette of Human Dicer.
Resolution
2.6 Å
Binding residue
(original residue number in PDB)
Y926 R927 F950 S952 Y961 Y962 Y966 W1014 Q1021 I1022
Binding residue
(residue number reindexed from 1)
Y156 R157 F180 S182 Y191 Y192 Y196 W228 Q235 I236
Enzymatic activity
Enzyme Commision number
3.1.26.3
: ribonuclease III.
Gene Ontology
Molecular Function
GO:0003723
RNA binding
View graph for
Molecular Function
External links
PDB
RCSB:4ngg
,
PDBe:4ngg
,
PDBj:4ngg
PDBsum
4ngg
PubMed
24486018
UniProt
Q9UPY3
|DICER_HUMAN Endoribonuclease Dicer (Gene Name=DICER1)
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