Structure of PDB 4ngf Chain A Binding Site BS01

Receptor Information
>4ngf Chain A (length=260) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QPCYLYVIGMVLTTPLPDELNFRRRKLYPPEDTTRCFGILTAKPIPQIPH
FPVYTRSGEVTISIELKKSGFMLSLQMLELITRLHQYIFSHILRYCVLPL
NVVSTLDIDFKFMEDIEKSETKETPFVFKLEDYQDAVIIPRYRNFDQPHR
FYVADVYTDLTPLSKFPSPEYETFAEYYKTKYNLDLTNLNQPLLDVDHTS
SRLNLLTPRPLSSAEKRKAKWESLQNKQILVPELCAIHPIPASLWRKAVC
LPSILYRLHC
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB4ngf A Phosphate-Binding Pocket within the Platform-PAZ-Connector Helix Cassette of Human Dicer.
Resolution3.101 Å
Binding residue
(original residue number in PDB)		Q931 H933 S984 K1011 W1014
Binding residue
(residue number reindexed from 1)		Q147 H149 S200 K218 W221
Enzymatic activity
Enzyme Commision number 3.1.26.3: ribonuclease III.
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:4ngf, PDBe:4ngf, PDBj:4ngf
PDBsum4ngf
PubMed24486018
UniProtQ9UPY3|DICER_HUMAN Endoribonuclease Dicer (Gene Name=DICER1)

[Back to BioLiP]