Structure of PDB 4ngd Chain A Binding Site BS01

Receptor Information
>4ngd Chain A (length=280) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QPCYLYVIGMVLTTPLPDELNFRRRKLYPPEDTTRCFGILTAKPIPQIPH
FPVYTRSGEVTISIELAASGFMLSLQMLELITRLHQYIFSHILRLEKPAL
AYCVLPLNVVSSTLDIDFKFMEDIEKSEARIGIPSTKYTKETPFVFKLED
YQDAVIIPRYRNFDQPHRFYVADVYTDLTPLSKFPSPEYETFAEYYKTKY
NLDLTNLNQPLLDVDHTSSRLNLLTPRHLPLSSAEKRKAKWESLQNKQIL
VPELCAIHPIPASLWRKAVCLPSILYRLHC
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4ngd A Phosphate-Binding Pocket within the Platform-PAZ-Connector Helix Cassette of Human Dicer.
Resolution1.958 Å
Binding residue
(original residue number in PDB)		Y926 R927 F950 F958 Y961 Y962 K965 Y966 S1006 W1014 L1017 Q1018 Q1021 I1022
Binding residue
(residue number reindexed from 1)		Y160 R161 F184 F192 Y195 Y196 K199 Y200 S233 W241 L244 Q245 Q248 I249
Enzymatic activity
Enzyme Commision number 3.1.26.3: ribonuclease III.
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:4ngd, PDBe:4ngd, PDBj:4ngd
PDBsum4ngd
PubMed24486018
UniProtQ9UPY3|DICER_HUMAN Endoribonuclease Dicer (Gene Name=DICER1)

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