Structure of PDB 4nf9 Chain A Binding Site BS01

Receptor Information

>4nf9 Chain A (length=216) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

RTEELLDQLSLSEWDVVEWSDDQAVFTFVYDTIQLTITFEESVVGFPFLD
KRYRKIVDVNFQSLLDEDQAPPSSLLVHKLIFQYVEEKESWKKTCTTQHQ
LPKMLEEFSLVVHHCRLLGEEIEYLKRWGPNYNLMNIDINNNELRLLFSS
SAAFAKFEITLFLSAYYPSVPLPSTIQNHVGNTSQDDIATILSKVPLENN
YLKNVVKQIYQDLFQD

Ligand information

>4nf9 Chain C (length=9) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

QRKWYPLRP

Receptor-Ligand Complex Structure

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Structure summary

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PDB	4nf9 Modular Assembly of RWD Domains on the Mis12 Complex Underlies Outer Kinetochore Organization.
Resolution	2.8 Å
Binding residue (original residue number in PDB)	V2124 Y2125 L2159 L2160 D2161 Q2164 A2165 P2166 S2169 E2218
Binding residue (residue number reindexed from 1)	V29 Y30 L64 L65 D66 Q69 A70 P71 S74 E123

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Biological Process
GO:0008608	attachment of spindle microtubules to kinetochore
GO:0034501	protein localization to kinetochore

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Biological Process

External links

PDB	RCSB:4nf9, PDBe:4nf9, PDBj:4nf9
PDBsum	4nf9
PubMed	24530301
UniProt	Q8NG31\|KNL1_HUMAN Kinetochore scaffold 1 (Gene Name=KNL1)

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