Structure of PDB 4nc7 Chain A Binding Site BS01

Receptor Information
>4nc7 Chain A (length=79) Species: 224308 (Bacillus subtilis subsp. subtilis str. 168) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KQYSQEELKEMALVEIAHELFEEHKKPVPFQELLNEIASLLGVKKEELGD
RIAQFYTDLNIDGRFLALSDQTWGLRSWY
Ligand information
Ligand IDI3C
InChIInChI=1S/C8H4I3NO4/c9-3-1(7(13)14)4(10)6(12)5(11)2(3)8(15)16/h12H2,(H,13,14)(H,15,16)
InChIKeyJEZJSNULLBSYHV-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0c1(c(c(c(c(c1I)N)I)C(=O)O)I)C(=O)O
CACTVS 3.341Nc1c(I)c(C(O)=O)c(I)c(C(O)=O)c1I
ACDLabs 10.04Ic1c(C(=O)O)c(I)c(c(I)c1N)C(=O)O
FormulaC8 H4 I3 N O4
Name5-amino-2,4,6-triiodobenzene-1,3-dicarboxylic acid;
5-Amino-2,4,6-triiodoisophthalic acid
ChEMBL
DrugBank
ZINCZINC000004806327
PDB chain4nc7 Chain A Residue 101 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB4nc7 X-ray vs. NMR structure of N-terminal domain of delta-subunit of RNA polymerase.
Resolution2.0 Å
Binding residue
(original residue number in PDB)		Q33 E34 N37 K47 Y81
Binding residue
(residue number reindexed from 1)		Q31 E32 N35 K45 Y79
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006351 DNA-templated transcription
GO:0006355 regulation of DNA-templated transcription

View graph for
Biological Process
External links
PDB RCSB:4nc7, PDBe:4nc7, PDBj:4nc7
PDBsum4nc7
PubMed24937760
UniProtP12464|RPOE_BACSU DNA-directed RNA polymerase subunit delta (Gene Name=rpoE)

[Back to BioLiP]