Structure of PDB 4n3u Chain A Binding Site BS01

Receptor Information
>4n3u Chain A (length=153) Species: 237561 (Candida albicans SC5314) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VSPSLIAKFEKTSKSNIEGTIKFTPANNGTVSVSVDLKGLPSDIGPFPYH
VHEKPVPASKNCSATENHFNPYNGTVRAATPAAHEVGDLAGKHGNIMGES
YKTEYDDSYISLNEKSRSYIGGLSIVIHANNGTRLNCANITLLDEGHGNA
NTT
Ligand information
Ligand IDCU
InChIInChI=1S/Cu/q+2
InChIKeyJPVYNHNXODAKFH-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Cu+2]
CACTVS 3.341[Cu++]
FormulaCu
NameCOPPER (II) ION
ChEMBL
DrugBankDB14552
ZINC
PDB chain4n3u Chain A Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB4n3u Candida albicans SOD5 represents the prototype of an unprecedented class of Cu-only superoxide dismutases required for pathogen defense.
Resolution1.75 Å
Binding residue
(original residue number in PDB)		H75 H77 H93 H153
Binding residue
(residue number reindexed from 1)		H50 H52 H68 H128
Annotation score1
Enzymatic activity
Enzyme Commision number 1.15.1.1: superoxide dismutase.
Gene Ontology
Molecular Function
GO:0005507 copper ion binding
GO:0046872 metal ion binding
Biological Process
GO:0006801 superoxide metabolic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:4n3u, PDBe:4n3u, PDBj:4n3u
PDBsum4n3u
PubMed24711423
UniProtQ5AD07|SOD5_CANAL Cell surface Cu-only superoxide dismutase 5 (Gene Name=SOD5)

[Back to BioLiP]