Structure of PDB 4ms8 Chain A Binding Site BS01

Receptor Information
>4ms8 Chain A (length=162) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MGPHSMRYYETATSPRYTSVGYVDDKEFVRFDSDAENPRYEPQVPWMEQE
GPEYWERITQIAKGQEQWFRVNLRTLLGYHTLQWMYGCDVGSDGRLLRGY
EQFAYDGCDYIALNEDLRTWTAADMAAQITRRKWEQAGAAEYYRAYLEGE
CVEWLHRYLKNG
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4ms8 Structural interplay between germline interactions and adaptive recognition determines the bandwidth of TCR-peptide-MHC cross-reactivity.
Resolution1.922 Å
Binding residue
(original residue number in PDB)
Y7 Y45 I63 Q70 W73 V76 N77 T80 W97 Y99 T143 W147 A150 A152 Y155 Y156 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)
Y8 Y40 I58 Q65 W68 V71 N72 T75 W84 Y86 T130 W134 A137 A139 Y142 Y143 Y146 W154 Y158
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:4ms8, PDBe:4ms8, PDBj:4ms8
PDBsum4ms8
PubMed26523866
UniProtP01897|HA1L_MOUSE H-2 class I histocompatibility antigen, L-D alpha chain (Gene Name=H2-L)

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