Structure of PDB 4mn8 Chain A Binding Site BS01

Receptor Information
>4mn8 Chain A (length=759) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SFEPEIEALKSFKNGISNDPLGVLSDWTIIGSLRHCNWTGITCDSTGHVV
SVSLLEKQLEGVLSPAIANLTYLQVLDLTSNSFTGKIPAEIGKLTELNQL
ILYLNYFSGSIPSGIWELKNIFYLDLRNNLLSGDVPEEICKTSSLVLIGF
DYNNLTGKIPECLGDLVHLQMFVAAGNHLTGSIPVSIGTLANLTDLDLSG
NQLTGKIPRDFGNLLNLQSLVLTENLLEGDIPAEIGNCSSLVQLELYDNQ
LTGKIPAELGNLVQLQALRIYKNKLTSSIPSSLFRLTQLTHLGLSENHLV
GPISEEIGFLESLEVLTLHSNNFTGEFPQSITNLRNLTVLTVGFNNISGE
LPADLGLLTNLRNLSAHDNLLTGPIPSSISNCTGLKLLDLSHNQMTGEIP
RGFGRMNLTFISIGRNHFTGEIPDDIFNCSNLETLSVADNNLTGTLKPLI
GKLQKLRILQVSYNSLTGPIPREIGNLKDLNILYLHSNGFTGRIPREMSN
LTLLQGLRMYSNDLEGPIPEEMFDMKLLSVLDLSNNKFSGQIPALFSKLE
SLTYLSLQGNKFNGSIPASLKSLSLLNTFDISDNLLTGTIPGELLASLKN
MQLYLNFSNNLLTGTIPKELGKLEMVQEIDLSNNLFSGSIPRSLQACKNV
FTLDFSQNNLSGHIPDEVFQGMDMIISLNLSRNSFSGEIPQSFGNMTHLV
SLDLSSNNLTGEIPESLANLSTLKHLKLASNNLKGHVPESGVFKNINASD
LMGNTDLCG
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4mn8 Structural basis for flg22-induced activation of the Arabidopsis FLS2-BAK1 immune complex.
Resolution3.062 Å
Binding residue
(original residue number in PDB)		Y148 R152 G174 M196 D220 R294 Y296 H316 S320 V340 H344 D393 D414 H417 S437 Q485
Binding residue
(residue number reindexed from 1)		Y123 R127 G149 M171 D195 R269 Y271 H291 S295 V315 H319 D368 D389 H392 S412 Q460
Enzymatic activity
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
External links
PDB RCSB:4mn8, PDBe:4mn8, PDBj:4mn8
PDBsum4mn8
PubMed24114786
UniProtQ9FL28|FLS2_ARATH LRR receptor-like serine/threonine-protein kinase FLS2 (Gene Name=FLS2)

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