Structure of PDB 4mfq Chain A Binding Site BS01

Receptor Information
>4mfq Chain A (length=323) Species: 1867 (Actinoplanes teichomyceticus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MDPETVRIALGLEERTAAWLTELDELGPPAEPVRLPRGEEARDLLRRLEV
PELDAEEIVAAAPDPDRDPALWWLLERTHHAIVRHMGDHRAKPRGGPPLP
YEGGAAARYFHVYVFLATVPAVRRFHAERGIPDEVGWETLTQLGELVAIH
RRKYGQGGMNMQWWTTYHLRGILYRLGRLQFSLATGKDGTPHLGLAVPEW
GGPLLPKAYDESLHRARPFFDRHFPEHGARVAWGSSWMLDPQLEEYLTED
SNIIQLARFWTLTDSAPEPGNADGDSSILEFVFRYNGQPLDELPQRSSLE
RAVIAHLKAGRHWHMRTGFVKLP
Ligand information
>4mfq Chain B (length=7) Species: 1867 (Actinoplanes teichomyceticus) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
GYIGGYI
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB4mfq Multiple complexes of long aliphatic N-acyltransferases lead to synthesis of 2,6-diacylated/2-acyl-substituted glycopeptide antibiotics, effectively killing vancomycin-resistant enterococcus
Resolution2.0 Å
Binding residue
(original residue number in PDB)		K92 P93 W163 Y167 S276 E280 F281
Binding residue
(residue number reindexed from 1)		K92 P93 W163 Y167 S276 E280 F281
Enzymatic activity
Enzyme Commision number 2.3.1.-
Gene Ontology
Molecular Function
GO:0016757 glycosyltransferase activity

View graph for
Molecular Function
External links
PDB RCSB:4mfq, PDBe:4mfq, PDBj:4mfq
PDBsum4mfq
PubMed25095906
UniProtQ70AY4

[Back to BioLiP]