Structure of PDB 4mdv Chain A Binding Site BS01

Receptor Information

>4mdv Chain A (length=351) Species: 6183 (Schistosoma mansoni) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

ISEFGITRSLIHSFDPHGKHYRPTIKPTTGFSASADAERLHRSMKGPGTN
ELAIINILARRTNYERQEICQSYKSLYKQDLKDDLKSDTSGDFRKVLCQL
IVDTPYMLAKSLYYAMKGLGTNDRVLIEIFTTLWNDEMKAVADAYKQVLK
DKGSEESERSLVTDMKKETCGDYEYALLSLVQAERDDIPILQLKAIPDKG
VNSIINHELAEADAKDLYASERRITRVICNRTPYQLYLTSEIYFKMYGKT
LLEHIESETSGDYRKLLVAVLRYAIDRPSLIAEWLHDSMAGLGTKDYALM
RLLITRSEIDLQDIMDAYESIYGKSLLNAVKDDTSGDYRRTLCVLMGEIY
N

Ligand information

Ligand ID

InChI

InChI=1S/Ca/q+2

InChIKey

BHPQYMZQTOCNFJ-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Ca++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Ca+2]

Formula

Name

CALCIUM ION

PDB chain

4mdv Chain A Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	4mdv Crystal structure and immunological properties of the first annexin from Schistosoma mansoni: insights into the structural integrity of the schistosomal tegument.
Resolution	2.5 Å
Binding residue (original residue number in PDB)	M49 K50 G51 G53 D93
Binding residue (residue number reindexed from 1)	M44 K45 G46 G48 D88
Annotation score	4

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0005509	calcium ion binding
GO:0005544	calcium-dependent phospholipid binding
GO:0042802	identical protein binding
GO:0046872	metal ion binding

	Cellular Component
GO:0005737	cytoplasm

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Molecular Function

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Cellular Component

External links

PDB	RCSB:4mdv, PDBe:4mdv, PDBj:4mdv
PDBsum	4mdv
PubMed	24428567
UniProt	C4QH88

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