Structure of PDB 4mda Chain A Binding Site BS01

Receptor Information
>4mda Chain A (length=200) Species: 7226 (Drosophila mauritiana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PHELNERQMERRKNTCEILLSRYKRKSFLHRIVTGDEKWIFFVKKTMLCV
WWDQSGVIYYELLKPGETVNAARYQQQLINLNRALQRKRPEYQKRQHRVI
FLHDNAPSHTARAVRDTLETLNWEVLPHAAYSPDLAPSDYHLFASMGHAL
AEQRFDSYESVKKWLDEWFAAKDDEFYWRGIHKLPERWEKCVASDGKYFE
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain4mda Chain A Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4mda Structural Basis of Mos1 Transposase Inhibition by the Anti-retroviral Drug Raltegravir.
Resolution1.7 Å
Binding residue
(original residue number in PDB)		D156 D249
Binding residue
(residue number reindexed from 1)		D36 D104
Annotation score4
Enzymatic activity
Enzyme Commision number 3.1.-.-
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding

View graph for
Molecular Function
External links
PDB RCSB:4mda, PDBe:4mda, PDBj:4mda
PDBsum4mda
PubMed24397848
UniProtQ7JQ07|MOS1T_DROMA Mariner Mos1 transposase (Gene Name=mariner\T)

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