Structure of PDB 4mbb Chain A Binding Site BS01

Receptor Information
>4mbb Chain A (length=184) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GPLGSNHIPERWKDYLPVGQRMPGTRFIAFKVPLQKSFEKKLAPEECFSP
LDLFNKIREQNEELGLIIDLTYTQRYYKPEDLPETVPYLKIFTVGHQVPD
DETIFKFKHAVNGFLKENKDNDKLIGVHSTHGLNRTGYLICRYLIDVEGV
RPDDAIELFNRCRGHCLERQNYIEDLQNGPIRKN
Ligand information
Ligand IDCL
InChIInChI=1S/ClH/h1H/p-1
InChIKeyVEXZGXHMUGYJMC-UHFFFAOYSA-M
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[Cl-]
FormulaCl
NameCHLORIDE ION
ChEMBL
DrugBankDB14547
ZINC
PDB chain4mbb Chain A Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4mbb Structure of Human PIR1, an Atypical Dual-Specificity Phosphatase.
Resolution1.849 Å
Binding residue
(original residue number in PDB)		T94 Y95 T96 R158
Binding residue
(residue number reindexed from 1)		T71 Y72 T73 R135
Annotation score3
Enzymatic activity
Enzyme Commision number 3.1.3.-
Gene Ontology
Biological Process
GO:0006470 protein dephosphorylation
GO:0016311 dephosphorylation

View graph for
Biological Process
External links
PDB RCSB:4mbb, PDBe:4mbb, PDBj:4mbb
PDBsum4mbb
PubMed24447265
UniProtO75319|DUS11_HUMAN RNA/RNP complex-1-interacting phosphatase (Gene Name=DUSP11)

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