Structure of PDB 4m2q Chain A Binding Site BS01

Receptor Information

>4m2q Chain A (length=188) Species: 9913 (Bos taurus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

GALSKEILEELQLNTKFTEEELSSWYQSFLKECPSGRITRQEFQTIYSKF
FPEADPKAYAQHVFRSFDANSDGTLDFKEYVIALHMTSAGKTNQKLEWAF
SLYDVDGNGTISKNEVLEIVTAIFKMISPEDTKHLPEDENTPEKRAEKIW
GFFGKKDDDKLTEKEFIEGTLANKEILRLIQFEPQKVK

Ligand information

Ligand ID

InChI

InChI=1S/Ca/q+2

InChIKey

BHPQYMZQTOCNFJ-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Ca++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Ca+2]

Formula

Name

CALCIUM ION

PDB chain

4m2q Chain A Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

Global view

Local view

Structure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

PDB	4m2q A Highly Conserved Cysteine of Neuronal Calcium-sensing Proteins Controls Cooperative Binding of Ca2+ to Recoverin.
Resolution	1.9 Å
Binding residue (original residue number in PDB)	D110 D112 N114 T116 E121
Binding residue (residue number reindexed from 1)	D104 D106 N108 T110 E115
Annotation score	4

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0005509	calcium ion binding
GO:0005515	protein binding
GO:0046872	metal ion binding

	Biological Process
GO:0007601	visual perception
GO:0007602	phototransduction
GO:0051924	regulation of calcium ion transport

	Cellular Component
GO:0001750	photoreceptor outer segment
GO:0001917	photoreceptor inner segment
GO:0005829	cytosol
GO:0016020	membrane
GO:0042995	cell projection
GO:0043204	perikaryon

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component

External links

PDB	RCSB:4m2q, PDBe:4m2q, PDBj:4m2q
PDBsum	4m2q
PubMed	24189072
UniProt	P21457\|RECO_BOVIN Recoverin (Gene Name=RCVRN)

[Back to BioLiP]