Structure of PDB 4lzm Chain A Binding Site BS01

Receptor Information

>4lzm Chain A (length=162) Species: 10665 (Tequatrovirus T4)

MNIFEMLRIDEGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAI
GRNCNGVITKDEAEKLFNQDVDAAVRGILRNAKLKPVYDSLDAVRRCALI
NMVFQMGETGVAGFTNSLRMLQQKRWDEAAVNLAKSRWYNQTPNRAKRVI
TTFRTGTWDAYK

Ligand information

• Ligand ID: CL
• InChI: InChI=1S/ClH/h1H/p-1
• InChIKey: VEXZGXHMUGYJMC-UHFFFAOYSA-M
• SMILES:
  ACDLabs 10.04
  CACTVS 3.341
  OpenEye OEToolkits 1.5.0: [Cl-]
• Formula: Cl
• Name: CHLORIDE ION
• DrugBank: DB14547
• PDB chain: 4lzm Chain A Residue 173

Receptor-Ligand Complex Structure

Structure summary

• PDB: 4lzm Comparison of the crystal structure of bacteriophage T4 lysozyme at low, medium, and high ionic strengths.
• Resolution: 1.7 Å
• Binding residue (original residue number in PDB): T142 N144
• Binding residue (residue number reindexed from 1): T142 N144
• Annotation score: 3

Enzymatic activity

• Catalytic site (original residue number in PDB): E11 D20
• Catalytic site (residue number reindexed from 1): E11 D20
• Enzyme Commision number: 3.2.1.17: lysozyme.

Gene Ontology

Molecular Function

• GO:0003796 lysozyme activity
• GO:0016798 hydrolase activity, acting on glycosyl bonds

Biological Process

• GO:0009253 peptidoglycan catabolic process
• GO:0016998 cell wall macromolecule catabolic process
• GO:0031640 killing of cells of another organism
• GO:0042742 defense response to bacterium
• GO:0044659 viral release from host cell by cytolysis

Cellular Component

• GO:0030430 host cell cytoplasm

External links

• PDB: RCSB:4lzm, PDBe:4lzm, PDBj:4lzm
• PDBsum: 4lzm
• PubMed: 2062826
• UniProt: P00720|ENLYS_BPT4 Endolysin (Gene Name=E)