Structure of PDB 4lkl Chain A Binding Site BS01
Receptor Information
>4lkl Chain A (length=214) Species:
9606
(Homo sapiens) [
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CHLSDMLQQLHSVNASKPSERGLVRQEEAEDPACIPIFWVSKWVDYSDKY
GLGYQLCDNSVGVLFNDSTRLILYNDGDSLQYIERDGTESYLTVSSHPNS
LMKKITLLKYFRNYMSEHLLKAGANITPLPYLRTWFRTRSAIILHLSNGS
VQINFFQDHTKLILCPLMAAVTYIDEKRDFRTYRLSLLEEYGCCKELASR
LRYARTMVDKLLSS
Ligand information
>4lkl Chain B (length=6) [
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PLHSTM
Receptor-Ligand Complex Structure
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PDB
4lkl
Exploring the binding nature of pyrrolidine pocket-dependent interactions in the polo-box domain of polo-like kinase 1
Resolution
1.58 Å
Binding residue
(original residue number in PDB)
K413 W414 D416 L490 L491 R516 F535 H538 K540
Binding residue
(residue number reindexed from 1)
K42 W43 D45 L119 L120 R137 F156 H159 K161
Enzymatic activity
Enzyme Commision number
2.7.11.21
: polo kinase.
External links
PDB
RCSB:4lkl
,
PDBe:4lkl
,
PDBj:4lkl
PDBsum
4lkl
PubMed
24223211
UniProt
P53350
|PLK1_HUMAN Serine/threonine-protein kinase PLK1 (Gene Name=PLK1)
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