Structure of PDB 4lez Chain A Binding Site BS01
Receptor Information
>4lez Chain A (length=359) Species:
10090
(Mus musculus) [
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KLKKVLDKLRLKRKDISEAAETVNKVVERLLRRMQKRESEFKGVEQLNTG
SYYEHVKISAPNEFDVMFKLEVPRIELQEYYETGAFYLVKFKRIPRGNPL
SHFLEGEVLSATKMLSKFRKIIKEEVKEIKDIDVSVEKEKPGSPAVTLLI
RNPEEISVDIILALESKGSWPISTKEGLPIQGWLGTKVRTNLRREPFYLV
PKNAKDGNSFQGETWRLSFSHTEKYILNNHGIEKTCCESSGAKCCRKECL
KLMKYLLEQLKKEFQELDAFCSYHVKTAIFHMWTQDPQDSQWDPRNLSSC
FDKLLAFFLECLRTEKLDHYFIPKFNLFSQELIDRKSKEFLSKKIEYERN
NGFPIFDKL
Ligand information
>4lez Chain E (length=18) [
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atctgtacatgtacagat
Receptor-Ligand Complex Structure
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PDB
4lez
Cyclic GMP-AMP Synthase Is Activated by Double-Stranded DNA-Induced Oligomerization.
Resolution
2.36 Å
Binding residue
(original residue number in PDB)
R158 L159 R161 H203 E386 K395
Binding residue
(residue number reindexed from 1)
R10 L11 R13 H55 E238 K247
Enzymatic activity
Enzyme Commision number
2.7.7.86
: cyclic GMP-AMP synthase.
External links
PDB
RCSB:4lez
,
PDBe:4lez
,
PDBj:4lez
PDBsum
4lez
PubMed
24332030
UniProt
Q8C6L5
|CGAS_MOUSE Cyclic GMP-AMP synthase (Gene Name=Cgas)
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