Structure of PDB 4l58 Chain A Binding Site BS01
Receptor Information
>4l58 Chain A (length=65) Species:
9606
(Homo sapiens) [
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DVTRCICGFTHDDGYMICCDKCSVWQHIDCMGIDRQHIPDTYLCERCQPR
NLDKERAVLLQRRKR
Ligand information
>4l58 Chain B (length=7) Species:
9606
(Homo sapiens) [
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ARTKQTA
Receptor-Ligand Complex Structure
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PDB
4l58
Molecular basis for chromatin binding and regulation of MLL5.
Resolution
1.48 Å
Binding residue
(original residue number in PDB)
D12 G14 Y15 M16 I17 W25 P39 D40
Binding residue
(residue number reindexed from 1)
D12 G14 Y15 M16 I17 W25 P39 D40
Enzymatic activity
Enzyme Commision number
2.1.1.43
: Transferred entry: 2.1.1.354.
External links
PDB
RCSB:4l58
,
PDBe:4l58
,
PDBj:4l58
PDBsum
4l58
PubMed
23798402
UniProt
Q8IZD2
|KMT2E_HUMAN Inactive histone-lysine N-methyltransferase 2E (Gene Name=KMT2E)
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