Structure of PDB 4l58 Chain A Binding Site BS01

Receptor Information
>4l58 Chain A (length=65) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DVTRCICGFTHDDGYMICCDKCSVWQHIDCMGIDRQHIPDTYLCERCQPR
NLDKERAVLLQRRKR
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB4l58 Molecular basis for chromatin binding and regulation of MLL5.
Resolution1.48 Å
Binding residue
(original residue number in PDB)
D12 G14 Y15 M16 I17 W25 P39 D40
Binding residue
(residue number reindexed from 1)
D12 G14 Y15 M16 I17 W25 P39 D40
Enzymatic activity
Enzyme Commision number 2.1.1.43: Transferred entry: 2.1.1.354.
External links
PDB RCSB:4l58, PDBe:4l58, PDBj:4l58
PDBsum4l58
PubMed23798402
UniProtQ8IZD2|KMT2E_HUMAN Inactive histone-lysine N-methyltransferase 2E (Gene Name=KMT2E)

[Back to BioLiP]