Structure of PDB 4l0z Chain A Binding Site BS01

Receptor Information
>4l0z Chain A (length=147) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VLADHPGELVRTDSPNFLCSVLPTHWRCNKTLPIAFKVVALGDVPDGTLV
TVMAGNDENYSAELRNATAAMKNQVARFNDLRFVGRSGRGKSFTLTITVF
TNPPQVATYHRAIKITVDGPREPRGSLSFSERLSELEQLRRTAMRVS
Ligand information
Receptor-Ligand Complex Structure
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PDB4l0z Structural basis of Ets1 activation by Runx1.
Resolution2.7 Å
Binding residue
(original residue number in PDB)		R139 R142 G143 K167 V170 D171
Binding residue
(residue number reindexed from 1)		R86 R89 G90 K114 V117 D118
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0005524 ATP binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4l0z, PDBe:4l0z, PDBj:4l0z
PDBsum4l0z
PubMed24646888
UniProtQ03347|RUNX1_MOUSE Runt-related transcription factor 1 (Gene Name=Runx1)

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