Structure of PDB 4kyw Chain A Binding Site BS01

Receptor Information
>4kyw Chain A (length=254) Species: 170187 (Streptococcus pneumoniae TIGR4) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MELHFNLELVETYKSNSQKARILTEDWVYRQSYCPNCGNNPLNHFENNRP
VADFYCNHCSEEFELKSKKGNFSSTINDGAYATMMKRVQADNNPNFFFLT
YTKNFEVNNFLVLPKQFVTPKSIIQRKPLAPTANRAGWIGCNIDLSQVPS
KGRIFLVQDGQVRDPEKVTKEFKQGLFLRKSSLSSRGWTIEILNCIDKIE
GSEFTLEDMYRFESDLKNIFVKNNHIKEKIRQQLQILRDKEIIEFKGRGK
YRKL
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB4kyw Structural basis of the methylation specificity of R.DpnI.
Resolution2.35 Å
Binding residue
(original residue number in PDB)		N16 S17 Q18 A20 R21 N48 D53 S67 K69 N77 G79 A80 Y101 R135 W138
Binding residue
(residue number reindexed from 1)		N16 S17 Q18 A20 R21 N48 D53 S67 K69 N77 G79 A80 Y101 R135 W138
Enzymatic activity
Enzyme Commision number 3.1.21.4: type II site-specific deoxyribonuclease.
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
GO:0009036 type II site-specific deoxyribonuclease activity
Biological Process
GO:0009307 DNA restriction-modification system

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:4kyw, PDBe:4kyw, PDBj:4kyw
PDBsum4kyw
PubMed24966351
UniProtP0A459|T2D1_STRPN Type II methyl-directed restriction enzyme DpnI (Gene Name=dpnC)

[Back to BioLiP]