Structure of PDB 4kmd Chain A Binding Site BS01

Receptor Information
>4kmd Chain A (length=367) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SLFPPGLHAIYGECRRLYPDQPNPLQVTAIVKYWLGGPDPLDYVSMYRNV
GSPSANIPEHWHYISFGLSDLYGDNRVHEFTGTDGPSGFGFELTFRLKRE
TGESAPPTWPAELMQGLARYVFQSENTFCSGDHVSWHSPLDNSESRIQHM
LLTEDPQMQPVQTPFGVVTFLQIVGVCTEELHSAQQWNGQGILELLRTVP
IAGGPWLITDMRRGETIFEIDPHLQERVDKGIETDGSNLSGVSAKCAWDD
LELIRTRQLESVHLKFNQESGALIPLCLRGRLLHGRHFTYKSITGDMAIT
FVSTGVEGAFATEEHPYAAHGPWLQILLTEEFVEKMLEDLEDLKLPKEYS
WPEKKLKVSILPDVVFD
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4kmd Structural insight into the mutual recognition and regulation between Suppressor of Fused and Gli/Ci.
Resolution1.7 Å
Binding residue
(original residue number in PDB)		Y147 T154 F155 G158 D159 H160 V161 S162 N265 L266 S267 G268 V269 S270 E376 K398
Binding residue
(residue number reindexed from 1)		Y120 T127 F128 G131 D132 H133 V134 S135 N238 L239 S240 G241 V242 S243 E269 K291
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0008134 transcription factor binding

View graph for
Molecular Function
External links
PDB RCSB:4kmd, PDBe:4kmd, PDBj:4kmd
PDBsum4kmd
PubMed24217340
UniProtQ9UMX1|SUFU_HUMAN Suppressor of fused homolog (Gene Name=SUFU)

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