Structure of PDB 4kis Chain A Binding Site BS01

Receptor Information
>4kis Chain A (length=315) Species: 272626 (Listeria innocua Clip11262) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DRMVMGKIKRIEAGLPLTTAKGRTFGYDVIDTKLYINEEEAKQLRLIYDI
FEEEQSITFLQKRLKKLGFKVRTYNRYNNWLTNDLYCGYVSYKDKVHVKG
IHEPIISEEQFYRVQEIFSRMGKNPNMNKESASLLNNLVVCSKCGLGFVH
RRKDTVSRGKKYHYRYYSCKTYKHTHELEKCGNKIWRADKLEELIIDRVN
NYSFASRNIDKEDESLNEKLKIEHAKKKRLFDLYINGSYEVSELDSMMND
IDAQINYYEAQIEANEELKKNKTVDFNSLEFREKQLYLKSLINKIYIDGE
QVTIEWLLEHHHHHH
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB4kis Attachment site recognition and regulation of directionality by the serine integrases.
Resolution3.2 Å
Binding residue
(original residue number in PDB)
R135 M136 G139 K140 R143 A153 K154 R156 S189 T191 Y207 M254 N261 K262 K286 S290 R291 Y295 Y297 Y299 H309
Binding residue
(residue number reindexed from 1)
R2 M3 G6 K7 R10 A20 K21 R23 S56 T58 Y74 M121 N128 K129 K153 S157 R158 Y162 Y164 Y166 H176
Binding affinityPDBbind-CN: Kd~20nM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000150 DNA strand exchange activity
GO:0003677 DNA binding

View graph for
Molecular Function
External links
PDB RCSB:4kis, PDBe:4kis, PDBj:4kis
PDBsum4kis
PubMed23821671
UniProtQ928V6

[Back to BioLiP]