Structure of PDB 4keg Chain A Binding Site BS01

Receptor Information
>4keg Chain A (length=535) Species: 9606,83333 [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQV
AATGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTWDAVRYN
GKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFN
LQEPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIK
NKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTF
KGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLG
AVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINA
ASGRQTVDEALAAAQTNAAASPTGLAGSLTNALSNGLLSGGLLGILENLP
LDIKVTDPQLLELGLVQSPDGHRLYVTIPLGIKLQVNLLRLAVKLDITAE
ILAVRDKQERIHLVLGDCTHSPGSLQISLLDLLDSLTGILNKVLPELVQG
NVCPLVNEVLRGLDITLVHDIVNMLIHGLQFVIKV
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain4keg Chain A Residue 1302 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4keg The Lipid Ligands of the SPLUNC1 Protein
Resolution2.5 Å
Binding residue
(original residue number in PDB)		P91 F92
Binding residue
(residue number reindexed from 1)		P91 F92
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0005515 protein binding
GO:0008289 lipid binding
GO:0015144 carbohydrate transmembrane transporter activity
GO:1901982 maltose binding
Biological Process
GO:0002395 immune response in nasopharyngeal-associated lymphoid tissue
GO:0006974 DNA damage response
GO:0008643 carbohydrate transport
GO:0015768 maltose transport
GO:0019731 antibacterial humoral response
GO:0034219 carbohydrate transmembrane transport
GO:0034289 detection of maltose stimulus
GO:0042742 defense response to bacterium
GO:0042956 maltodextrin transmembrane transport
GO:0043129 surfactant homeostasis
GO:0045087 innate immune response
GO:0050891 multicellular organismal-level water homeostasis
GO:0051607 defense response to virus
GO:0055085 transmembrane transport
GO:0060326 cell chemotaxis
GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide
GO:1900229 negative regulation of single-species biofilm formation in or on host organism
GO:1902305 regulation of sodium ion transmembrane transport
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0016020 membrane
GO:0030288 outer membrane-bounded periplasmic space
GO:0042597 periplasmic space
GO:0043190 ATP-binding cassette (ABC) transporter complex
GO:0055052 ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
GO:1990060 maltose transport complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4keg, PDBe:4keg, PDBj:4keg
PDBsum4keg
PubMed
UniProtP0AEX9|MALE_ECOLI Maltose/maltodextrin-binding periplasmic protein (Gene Name=malE);
Q9NP55

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