Structure of PDB 4ka7 Chain A Binding Site BS01

Receptor Information
>4ka7 Chain A (length=695) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SDETLSSNPLLQDFDFPPFDSVDASHVRPGIRALLQHLEAELEELEKSVE
PTWPKLVEPLEKIVDRLTVVWGMINHLKAVKDTPELRAAIEDVQPEKVKF
QLRLGQSKPIYNAFKAIRESPDWSSLSEARQRLVEAQIKEAVLIGIALDD
EKREEFNKIEQELEKLSHKFSENVLDATKKFEKLITDKKEIEGLPPSALG
LFAQAAVSKGHENATAENGPWIITLDAPSYLPVMQHAKNRALREEVYRAY
LSRASSGDLDNTAIIDQILKLRLEKAKLLGYNNYAEVSMAMKMATVEKAA
ELLEKLRSASWDAAVQDMEDLKSFAKNQGAAESDSMTHWDTTFWSERLRE
SKYDINEEELRPYFSLPKVMDGLFSLAKTLFGIDIEPADGLAPVWNNDVR
FYRVKDSSGNPIAYFYFDPYSRPSEKRGGAWMDEVVSRSRVMAQKGSSVR
LPVAHMVCNQTPPVGDKPSLMTFREVETVFHQFGHALQHMLTKQDEGLVA
GIRNIEWDAVELPSQFMENWCYHRDTLMSIAKHYETGETLPEEVYKKLLA
ARTFRAGSFSLRQLKFASVDLELHTKYVPGGPESIYDVDQRVSVKTQVIP
PLPEDRFLCSFSHIFAGGYAAGYYSYKWAEVLSADAFSAFEDAGLDDIKA
VKETGQRFRNTILALGGGKAPLKVFVEFRGREPSPEPLLRHNGLL
Ligand information
Receptor-Ligand Complex Structure
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PDB4ka7 Organellar oligopeptidase (OOP) provides a complementary pathway for targeting peptide degradation in mitochondria and chloroplasts.
Resolution1.8 Å
Binding residue
(original residue number in PDB)		A520 W521 M522 H571 H575 W597 H703 Y716
Binding residue
(residue number reindexed from 1)		A430 W431 M432 H481 H485 W507 H613 Y626
Enzymatic activity
Catalytic site (original residue number in PDB) H571 Q572 H575 E601 Y716
Catalytic site (residue number reindexed from 1) H481 Q482 H485 E511 Y626
Enzyme Commision number 3.4.24.70: oligopeptidase A.
Gene Ontology
Molecular Function
GO:0004222 metalloendopeptidase activity
GO:0008233 peptidase activity
GO:0008237 metallopeptidase activity
GO:0046872 metal ion binding
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0005829 cytosol
GO:0009507 chloroplast
GO:0009536 plastid
GO:0009570 chloroplast stroma

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4ka7, PDBe:4ka7, PDBj:4ka7
PDBsum4ka7
PubMed24043784
UniProtQ94AM1|OOPDA_ARATH Organellar oligopeptidase A, chloroplastic/mitochondrial (Gene Name=OOP)

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