Structure of PDB 4ka2 Chain A Binding Site BS01
Receptor Information
>4ka2 Chain A (length=337) Species:
11676
(Human immunodeficiency virus 1) [
Search protein sequence
] [
Download receptor structure
] [
Download structure with residue number starting from 1
] [
View receptor structure
]
VWKEATTTLFCASDAKAYDTEVHNVWATHACVPTDPNPQEVKLENVTENF
NMWKNNMVEQMHEDIISLWDQSLKPCVKLTGGSVITQACPKVSFEPIPIH
YCAPAGFAILKCNDKKFNGTGPCTNVSTVQCTHGIRPVVSTQLLLNGSLA
EEEIVIRSENFTNNAKTIIVQLNESVVINCTRPNNGDIRQAHCNLSKTQW
ENTLEQIAIKLKEQFGNNKTIIFNPSSGGDPEIVTHSFNCGGEFFYCNST
QLFTWNDTGRNITLPCRIKQIINMWQEVGKAMYAPPIRGQIRCSSNITGL
LLTRDGGNGTEIFRPGGGDMRDNWRSELYKYKVVKIE
Ligand information
>4ka2 Chain R (length=27) [
Search peptide sequence
] [
Download ligand structure
] [
Download structure with residue number starting from 1
] [
View ligand structure
]
CNLHFCQLRCKSLGLLGRCAPTFCACV
Receptor-Ligand Complex Structure
Global view
Local view
Structure summary
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
PDB
4ka2
Interfacial Cavity Filling To Optimize CD4-Mimetic Miniprotein Interactions with HIV-1 Surface Glycoprotein.
Resolution
1.79 Å
Binding residue
(original residue number in PDB)
A281 S365 G366 G367 D368 E370 I371 S375 F376 F382 N425 M426 W427 E429 G473
Binding residue
(residue number reindexed from 1)
A165 S227 G228 G229 D230 E232 I233 S237 F238 F244 N273 M274 W275 E277 G318
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Cellular Component
GO:0019031
viral envelope
View graph for
Cellular Component
External links
PDB
RCSB:4ka2
,
PDBe:4ka2
,
PDBj:4ka2
PDBsum
4ka2
PubMed
23710622
UniProt
P35961
|ENV_HV1Y2 Envelope glycoprotein gp160 (Gene Name=env)
[
Back to BioLiP
]