Structure of PDB 4k74 Chain A Binding Site BS01

Receptor Information
>4k74 Chain A (length=357) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HMKFTVEREHLLKPLQQVSGPLLPILGNLLLQVADGTLSLTGTDLEMEMV
ARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRS
RFSLSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYY
LNGMLFETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELM
RMLDNPLRVQIGSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLE
AGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQEEAEEILD
VTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSA
AYVVMPM
Ligand information
Receptor-Ligand Complex Structure
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PDB4k74 The UmuC subunit of the E. coli DNA polymerase V shows a unique interaction with the beta-clamp processivity factor.
Resolution2.5 Å
Binding residue
(original residue number in PDB)		G174 H175 R246 Y323 M362 P363
Binding residue
(residue number reindexed from 1)		G170 H171 R239 Y316 M355 P356
Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0008408 3'-5' exonuclease activity
Biological Process
GO:0006260 DNA replication
GO:0006271 DNA strand elongation involved in DNA replication
GO:0071897 DNA biosynthetic process
Cellular Component
GO:0005737 cytoplasm
GO:0009360 DNA polymerase III complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4k74, PDBe:4k74, PDBj:4k74
PDBsum4k74
PubMed23822808
UniProtQ1R4N6

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