Structure of PDB 4k45 Chain A Binding Site BS01
Receptor Information
>4k45 Chain A (length=102) Species:
10116
(Rattus norvegicus) [
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QAESKEWYHASLTRAQAEHMLMRVPRDGAFLVRKRNEPNSYAISFRAEGK
IKHCRVQQEGQTVMLGNSEFDSLVDLISYYEKHPLYRKMKLRYPINEEAL
EK
Ligand information
>4k45 Chain B (length=8) Species:
10116
(Rattus norvegicus) [
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PGFYVEAN
Receptor-Ligand Complex Structure
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PDB
4k45
Autoinhibition and Phosphorylation-Induced Activation of Phospholipase C-gamma Isozymes.
Resolution
1.5 Å
Binding residue
(original residue number in PDB)
R675 R694 R696 H714 R716 L726 L746 Y747 R748
Binding residue
(residue number reindexed from 1)
R14 R33 R35 H53 R55 L65 L85 Y86 R87
Enzymatic activity
Enzyme Commision number
3.1.4.11
: phosphoinositide phospholipase C.
External links
PDB
RCSB:4k45
,
PDBe:4k45
,
PDBj:4k45
PDBsum
4k45
PubMed
23777354
UniProt
P10686
|PLCG1_RAT 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (Gene Name=Plcg1)
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