Structure of PDB 4k0a Chain A Binding Site BS01

Receptor Information
>4k0a Chain A (length=337) Species: 11676 (Human immunodeficiency virus 1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VWKEATTTLFCASDAKAYDTEVHNVWATHACVPTDPNPQEVKLENVTENF
NMWKNNMVEQMHEDIISLWDQSLKPCVKLTGGSVITQACPKVSFEPIPIH
YCAPAGFAILKCNDKKFNGTGPCTNVSTVQCTHGIRPVVSTQLLLNGSLA
EEEIVIRSENFTNNAKTIIVQLNESVVINCTRPNNDIRQAHCNLSKTQWE
NTLEQIAIKLKEQFGNNKTIIFNPSSGGDPEIVTHSFNCGGEFFYCNSTQ
LFTWNDTGRNITLPCRIKQIINMWQEVGKAMYAPPIRGQIRCSSNITGLL
LTRDGGKNGTEIFRPGGGDMRDNWRSELYKYKVVKIE
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4k0a Structural Basis for Highly Effective HIV-1 Neutralization by CD4-Mimetic Miniproteins Revealed by 1.5 A Cocrystal Structure of gp120 and M48U1.
Resolution2.13 Å
Binding residue
(original residue number in PDB)
V255 A281 G366 G367 D368 E370 I371 F382 M426 W427 E429 G473
Binding residue
(residue number reindexed from 1)
V139 A165 G227 G228 D229 E231 I232 F243 M273 W274 E276 G318
Enzymatic activity
Enzyme Commision number ?
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:4k0a, PDBe:4k0a, PDBj:4k0a
PDBsum4k0a
PubMed23707685
UniProtP35961|ENV_HV1Y2 Envelope glycoprotein gp160 (Gene Name=env)

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