Structure of PDB 4jre Chain A Binding Site BS01

Receptor Information
>4jre Chain A (length=409) Species: 83333 (Escherichia coli K-12) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AVITDWRPEDPAFWQQRGQRIASRNLWISVPCLLLAFCVWMLFSAVAVNL
PKVGFNFTTDQLFMLTALPSVSGALLRVPYSFMVPIFGGRRWTAFSTGIL
IIPCVWLGFAVQDTSTPYSVFIIISLLCGFAGANFASSMANISFFFPKQK
QGGALGLNGGLGNMGVSVMQLVAPLVVSYLANASWIWVPFLAIFTIAAWF
GMNDLALWIMSLLYLATFGSFIGFSAGFAMLSKTQFPDVQILQYAFFGPF
IGALARSAGGALSDRLGGTRVTLVNFILMAIFSGLLFLTLPTDGQGGSFM
AFFAVFLALFLTAGLGSGSTFQMISVIFRKLTMDRVKAEGGSDERAMREA
ATDTAAALGFISAIGAIGGFFIPKAFGSSLALTGSPVGAMKVFLIFYIAC
VVITWAVYG
Ligand information
Ligand IDNO2
InChIInChI=1S/HNO2/c2-1-3/h(H,2,3)/p-1
InChIKeyIOVCWXUNBOPUCH-UHFFFAOYSA-M
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341		[O-]N=O
OpenEye OEToolkits 1.5.0N(=O)[O-]
FormulaN O2
NameNITRITE ION
ChEMBL
DrugBankDB12529
ZINC
PDB chain4jre Chain A Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4jre Crystal structure of a nitrate/nitrite exchanger.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		R89 F147 Y263 F267
Binding residue
(residue number reindexed from 1)		R77 F135 Y214 F218
Annotation score5
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005452 solute:inorganic anion antiporter activity
GO:0015112 nitrate transmembrane transporter activity
GO:0015113 nitrite transmembrane transporter activity
GO:0022857 transmembrane transporter activity
Biological Process
GO:0015706 nitrate transmembrane transport
GO:0015707 nitrite transport
GO:0042128 nitrate assimilation
GO:0043602 nitrate catabolic process
GO:0055085 transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4jre, PDBe:4jre, PDBj:4jre
PDBsum4jre
PubMed23665960
UniProtP10903|NARK_ECOLI Nitrate/nitrite antiporter NarK (Gene Name=narK)

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