Structure of PDB 4joe Chain A Binding Site BS01

Receptor Information
>4joe Chain A (length=87) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GPIRKVLLLKEDHEGLGISITGGKEHGVPILISEIHPGQPADRCGGLHVG
DAILAVNGVNLRDTKHKEAVTILSQQRGEIEFEVVYV
Ligand information
Receptor-Ligand Complex Structure
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PDB4joe Stereochemical Preferences Modulate Affinity and Selectivity among Five PDZ Domains that Bind CFTR: Comparative Structural and Sequence Analyses.
Resolution1.14 Å
Binding residue
(original residue number in PDB)
G298 L299 G300 I301 S302 I303 T304 G305 H309 V311 H349 V353 L356
Binding residue
(residue number reindexed from 1)
G15 L16 G17 I18 S19 I20 T21 G22 H26 V28 H66 V70 L73
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Cellular Component
GO:0005794 Golgi apparatus

View graph for
Cellular Component
External links
PDB RCSB:4joe, PDBe:4joe, PDBj:4joe
PDBsum4joe
PubMed24210758
UniProtQ9HD26|GOPC_HUMAN Golgi-associated PDZ and coiled-coil motif-containing protein (Gene Name=GOPC)

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