Structure of PDB 4iwf Chain A Binding Site BS01
Receptor Information
>4iwf Chain A (length=236) Species:
9606
(Homo sapiens) [
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SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILL
NSGVYTFEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILS
HIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR
Ligand information
>4iwf Chain C (length=10) Species:
9606
(Homo sapiens) [
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HKILHRLLQD
Receptor-Ligand Complex Structure
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PDB
4iwf
Ligand binding dynamics rewire cellular signaling via Estrogen Receptor-alpha
Resolution
1.932 Å
Binding residue
(original residue number in PDB)
I358 K362 L372 Q375 E380 D538 E542
Binding residue
(residue number reindexed from 1)
I54 K58 L68 Q71 E76 D226 E230
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:4iwf
,
PDBe:4iwf
,
PDBj:4iwf
PDBsum
4iwf
PubMed
23524984
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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