Structure of PDB 4iw8 Chain A Binding Site BS01
Receptor Information
>4iw8 Chain A (length=239) Species:
9606
(Homo sapiens) [
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SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRNQGKCVMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNS
GVYTFTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLL
ILSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR
Ligand information
>4iw8 Chain C (length=10) Species:
9606
(Homo sapiens) [
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HKILHRLLQD
Receptor-Ligand Complex Structure
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PDB
4iw8
Ligand binding dynamics rewire cellular signaling via Estrogen Receptor-alpha
Resolution
2.0375 Å
Binding residue
(original residue number in PDB)
I358 L372 V376 L379 E380 E542 M543
Binding residue
(residue number reindexed from 1)
I54 L68 V72 L75 E76 E233 M234
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:4iw8
,
PDBe:4iw8
,
PDBj:4iw8
PDBsum
4iw8
PubMed
23524984
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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