Structure of PDB 4ivy Chain A Binding Site BS01
Receptor Information
>4ivy Chain A (length=229) Species:
9606
(Homo sapiens) [
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NSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRE
LVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLL
FAPNLLLDRNQVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNS
GVYDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSN
KGMEHLYSMKCKNVVPLSDLLLEMLDAHR
Ligand information
>4ivy Chain C (length=10) Species:
9606
(Homo sapiens) [
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HKILHRLLQD
Receptor-Ligand Complex Structure
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PDB
4ivy
Ligand binding dynamics rewire cellular signaling via Estrogen Receptor-alpha
Resolution
1.95 Å
Binding residue
(original residue number in PDB)
I358 K362 L372 V376 E380 L539 E542
Binding residue
(residue number reindexed from 1)
I55 K59 L69 V73 E77 L220 E223
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:4ivy
,
PDBe:4ivy
,
PDBj:4ivy
PDBsum
4ivy
PubMed
23524984
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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