Structure of PDB 4ivw Chain A Binding Site BS01
Receptor Information
>4ivw Chain A (length=234) Species:
9606
(Homo sapiens) [
Search protein sequence
] [
Download receptor structure
] [
Download structure with residue number starting from 1
] [
View receptor structure
]
KNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADR
ELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKL
LFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSII
LLNSGVYTDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHI
RHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR
Ligand information
>4ivw Chain C (length=10) Species:
9606
(Homo sapiens) [
Search peptide sequence
] [
Download ligand structure
] [
Download structure with residue number starting from 1
] [
View ligand structure
]
HKILHRLLQD
Receptor-Ligand Complex Structure
Global view
Local view
Structure summary
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
PDB
4ivw
Ligand binding dynamics rewire cellular signaling via Estrogen Receptor-alpha
Resolution
2.06 Å
Binding residue
(original residue number in PDB)
I358 K362 V376 E380 D538 L539 E542
Binding residue
(residue number reindexed from 1)
I56 K60 V74 E78 D224 L225 E228
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:4ivw
,
PDBe:4ivw
,
PDBj:4ivw
PDBsum
4ivw
PubMed
23524984
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
[
Back to BioLiP
]
